EGF and cancer: The Illumina annotated gene set, which included a larger number of genes annotated to more MSDP-associated CpGs, was additionally enriched with numerous pathways involving growth factor signaling (FGFR, EGF-EGFR, and PDGFR), hormones (aldosterone, insulin, and TSH), immune and inflammatory signaling (IL2 and IL6), MAPK signaling, myometrial and vascular smooth muscle contraction, signal transduction, and cancer pathways.