GSDMD and Carcinoma, Lewis Lung: When activated OT-1 T cells were co-cultured with ovalbumin-expressing Lewis lung carcinoma (3LL-OVA) cells, the co-localization of GSDMD and GzmB was observed in the CTLs near their immune synapses; moreover, CTL cytotoxicity towards 3LL-OVA cells was diminished following GSDMD knockdown.