CD4 and endometriosis: In order to explore whether rhIL-37 improves endometriosis through increasing Th1/Th2 ratio by inducing DCs maturation, we separated CD4+T cells successfully from the peripheral blood of healthy mice (Supplementary Fig. 2), and DCs from the peripheral blood of healthy mice (control-DCs) and mouse with endometriosis (EMs-DCs) (Supplementary Fig. 3).