To the best of our knowledge, this is the first study evaluating the potential association of haplotypes of VEGF −2578C/A (rs699947), −2549I/D (rs35569394), −460T/C (rs833061), +405C/G (rs2010963) −7C/T (rs25648) and +936C/T (rs3025039) polymorphism with breast cancer risk. Here, VEGFA is linked to breast cancer.