A series of studies have demonstrated that transforming growth factor (TGF)-β1 is an important pro-fibrotic growth factor that is involved in the upstream regulation of various biological processes and signaling pathways and directly stimulates cardiac fibroblasts proliferation; the TGF-β1 pathway induces myocardial fibrosis in response to various factors [7]. Here, TGFB1 is linked to Myocardial fibrosis.