ATXN3 and Alzheimer disease: TBP has also been linked to the key pathological features of some neurodegenerative disorders, including neuronal intranuclear hyaline inclusion disease (NIH-ID) [37], spinocerebellar ataxia types 1, 2, 3 (SCA1, SCA2, SCA3) [38,39], dentatorubral-pallidoluysian atrophy (DRPLA) [38], Huntington’s disease (HD) [40], and Alzheimer’s disease (AD) [41].