The adjusted OR for neonatal hypoglycaemia was 0.4, 0.3 and 0.3 for 1st, 2nd and 3rd trimester exposure, respectively (p = 0.07; p = 0.03; p = 0.05, respectively), after adjustment for insulin use, gestational age and LGA (Table 2). The gene discussed is INS; the disease is Hypoglycemia.