CEACAM5 and neoplasm: To further evaluate the accuracy of our circulating 5-miRNA signature compared with other clinical factors, we performed univariate and multivariate analyses, which revealed that our miRNA biomarker signature had superior diagnostic power vs other clinical features, including age, sex, and the 2 most commonly used GC tumor markers, CEA and CA19-9 (eTable 6 in the Supplement).