ODCs that are recorded by several data points over the whole range of the curve, however, would actually be needed to reveal high O2‐affinity hemoglobinopathies with impaired cooperativity (Mangin, 2017) or any structural or functional pathology in Hb in general that is not easily detected with an algorithmic one‐point estimation of P50. Here, GSTM1 is linked to hemoglobinopathy.