Moreover, some studies have shown that miRNA-2 promoted carcinogenic activity by upregulating the expression of RAN in HCC cells [34]; the high expression of HNRNPA1 promoted the invasion of gastric cancer cells [35]; lncRNA CDKN2B-AS1 promoted the growth of HCC by regulating the let-7c-5p/NAP1L1 axis [36]. Here, RAN is linked to hepatocellular carcinoma.