SOX10 and Waardenburg syndrome type 2: In the present study, we provide details about a Chinese patient with WS2, and noted a de novo heterozygous mutation in SOX10. Patient-derived fibroblasts were gathered to produce iPSCs, and we then differentiated these iPSCs into NCCs in vitro, and contrasted their differentiation potential with iPSCs derived from a normal healthy patient to examine disorders linked to this syndrome.