ERBB2 and gastric cancer: On the basis of a favourable safety profile and an 18% confirmed overall response rate (RR) in a phase I-study in pre-treated patients with gastroesophageal cancer, FIGHT (NCT03343301), a global, double-blind, randomised phase II trial evaluating Bemarituzumab was conducted in chemo naive patients with HER2 negative, advanced or metastatic GC and centrally confirmed either FGFR2b overexpression by immunohistochemistry or -amplification by circulating tumour DNA [2].