Finally, an ongoing study with margetuximab combined with anti-PD-1 (retifanlimab) or anti-PD-1/LAG-3 (tebotelimab) ± chemotherapy in first-line therapy of advanced/metastatic HER2 + gastroesophageal junction (GEJ) or gastric cancer (GC) deserves mention [52]. Here, LAG3 is linked to gastric cancer.