UBE2L3 and Hypoglycemia: Another ubiquitin enzyme UBE2L3 was also decreased from 0.5-h to 4-h post-hypoglycemia (Fig. 4D), however, the significant differences were observed at 0.5-h, 2-h and 4-h [UBE2L3 (RFU): (784.9 ± 35.1 vs 945.6 ± 49.3 0.5-h post-hypoglycemia vs baseline; 760.5 ± 40.8 vs 945.6 ± 49.3 2-h post-hypoglycemia vs baseline, p < 0.01; 760.0 ± 52.0 vs 945.6 ± 49.3, 4-h post-hypoglycemia vs baseline, p < 0.01].