ADAM15 and hepatocellular carcinoma: To further verify the effect of ADAM15 expression on the survival of HCC patients, we performed survival analysis by the Kaplan Meier plotter online database, our findings revealed that ADAM15 expression was related to OS (P = 0.0074), RFS (P = 0.012) and Progress Free Survival (PFS) (P = 0.026) (Supplementary Figure 1A–1C), and was not correlated with Disease Free Survival (DSS) (P > 0.05) (Supplementary Figure 1D).