As presented in Fig. 3c, d, several cytokines and chemokines, namely KC, MCP1, IL6 and RANTES, were significantly higher in medium of MCC treated with total CP secretome from mice injected with AβO compared to the scrambled condition, whereas also the gene expression of Kc, Mcp1 and Il6 was significantly upregulated in the MCC cells. The gene discussed is CP; the disease is Merkel cell skin cancer.