In a mouse endometriosis model, bazedoxifene [139], an estrogen receptor modulator, administered with the conjugated estrogens and letrozole [143] (aromatase inhibitor) not only alleviated the lesions of endometriosis, but also dramatically reduced the recruitment of BMDSCs to the lesions and restore the stem cell engraftment of the uterine endometrium. Here, CYP19A1 is linked to endometriosis.