INS and type 2 diabetes mellitus: In addition, ADCY5 was also inferred as the effector gene for SNPs rs11708903, rs6438788, and rs4450740 associated with blood glucose and insulin-secreting cells and residing in the intronic region of ADCY5. Finally, supporting data for KCNQ1, a susceptibility gene for type 2 diabetes [72], is provided in Additional file 1: Figure S49.