JIA patients demonstrate high levels of TNFα, MIF, macrophage inflammatory protein (CCL3), macrophage-derived chemokine (CCL22), monokine induced by IFNγ (CXCL9), monocyte chemoattractant protein-1 (CCL2) and IFNγ-induced protein-10 (CXCL10) in blood and synovial fluid [32]. Here, CCL22 is linked to juvenile idiopathic arthritis.