APOE and atherosclerosis: Evaluation of atherosclerosis in aortic roots and throughout the aorta of the bone marrow–recipient mice 8 weeks after feeding the Western diet showed that apoE3 bone marrow–recipient mice developed smaller atherosclerotic lesions in the aortic roots (Fig. 10, A and B) and the whole aorta (Fig. 10C) than recipients of apoE2, apoE4, or apoE-deficient bone marrow cells.