Importantly, endogenous Merlin co-immunoprecipitated with the PAFC components as well as CHD1 and VPRBP in IOMM-Lee meningioma cells [45] (Fig 1C), confirming that these interactions take place at physiological levels of Merlin as well as in the absence of SV40 Large T antigen that is expressed in HEK293T cells [46]. Here, NF2 is linked to meningioma.