In contrast, a subsequent analysis of the ERICH data with propensity score matching for hypertension and adjusting only for age and sex found APOE ɛ4 to be associated with lobar ICH in Hispanic populations as well.31 When restricted to case and control participants with lobar ICH aged 60 years and older, we found APOE ɛ4 to be associated with ICH in Hispanic but not Black participants. This evidence concerns the gene APOE and hypertensive disorder.