CD8A and influenza: To elucidate the transcriptional states of the differentially expanded T cell subsets between CAP-flu and CAP-other patients, we examined the top DEGs between CD8 EM T and CD8 EMRA-like cells (Figure 2d): among the top upregulated genes in the CD8 EM-cluster, we identified GZMK and genes related to MHC class II (HLD-DRB1 and CD74).