Moreover, the co‐regulation of MYC, the CPC and its counteracting phosphatase Repo‐Man (CDCA2) by H2A.Z.1 we have here reported, provides further support to the important role of these complexes in cancer where the co‐upregulation of Repo‐Man and Aurora B in tumours is inversely correlated with patient survival (Manzione et al, 2020). This evidence concerns the gene MYC and cancer.