The virus enters the host cell by binding its spike protein to angiotensin‐converting enzyme 2 (ACE2) on human cells.[9] TMPRSS2 helps to activate the spike protein on SARS‐CoV‐2.[10] After entering host cells, the virus can not only cause inflammation and immune disorders but also destroy the upper respiratory tract microbial balance. This evidence concerns the gene ACE2 and immune system disorder.