Study also reported that LCN2 is released from various cell types and upregulated in tissue damaging conditions such as ulcerative colitis, infection and burn injury.6 27 It has been conceded as an promising biomarker of inflammation, infection, ischaemia as well as kidney damage.6 LCN2 is highly expressed in intestinal epithelial cell in case of inflammatory bowel disease.6 Moreover, it has been reported as a dynamic and sensitive biomarker of gut inflammation.33 Besides, LCN2 also positively correlated with EED score. The gene discussed is LCN2; the disease is inflammatory response.