In accordance with our results, recent studies have reported that CUX1 overexpression was significantly associated with tumorigenesis and poor prognosis in patients with multiple myeloma, uterine leiomyomas, colorectal cancer, and high-grade breast cancer (Moon et al., 2002; Cancer Genome Atlas, 2012; Vadnais et al., 2014). Here, CUX1 is linked to colorectal cancer.