Interestingly, we observed that sVCAM-1 was highly correlated with GM-CSF, the TH1 chemokine CXCL10 and IL-10, which our team and others recently identified as the peculiar “cytokine/chemokine signature” associated with poorer outcome in COVID-19 patients (13, 14, 16). The gene discussed is IL10; the disease is COVID-19.