For LUSC patients (Figures 4C,D), compared with tumor tissues with low DC1 abundance, PD-L1, IDO1, CTLA4, LAG3, CD70, HAVCR2, CD40, CD47, TIGIT, and TNFSF14 were significantly increased in low DC1 infiltration tumor tissues. The gene discussed is LAG3; the disease is neoplasm.