AKT1 and lung adenocarcinoma: Metastasis-associated transcriptome 1(MALAT-1) of lung adenocarcinoma (Gutschner et al., 2013; Xu et al., 2015), whose abnormal expression can not only affect the invasion and metastasis of breast cancer cells, but also affect the EMT of breast cancer cells by regulating PI3K-Akt signaling pathway.