TLR3 and lip and oral cavity carcinoma: Toll-like receptor 3 (TLR3) stimulation of oral cancer cells can cause tumor progression (Urban-Wojciuk et al., 2019), which is evidenced by the fact that the stimulation of TLR3-expressing oral cancer cells lines (buccal OC2 cancer cells) was found to lead to tumor progression via the production of immunosuppressive factors (Chuang et al., 2012).