Figures 10C,D show the distribution of ZC3H13 in infiltrating immune cells of TIME. Based on previous findings, CD4-c6-FOXP3 corresponded to regulatory T (Treg) cells (Guo et al., 2018), suggesting that ZC3H13 may serve as an opposing player in HCC progression. This evidence concerns the gene ZC3H13 and hepatocellular carcinoma.