HLA-C and hepatocellular carcinoma: The difference in immune-related signature between clusters 1 and 2 was that subtype 2 was closely correlated with higher aDCs and MHC class I, whereas subtype 1 experienced more neutrophils, B cells, pDCs, NK cells, DCs, mast cells, cytolytic activity, TIL, and Type I/II IFN response, indicating that the distinction of m6A regulators’ expression pattern significantly correlated with TIME characterization of HCC (Figure 3F and Supplementary Figure 1E).