In humans, low expression or inactivation of ATM causes ataxia-telangiectasia (A-T), a neurodegenerative syndrome associated with growth retardation, cancer predisposition, immune response deficiency, and genomic instability (Savitsky et al., 1995; Rothblum-Oviatt et al., 2016). Here, ATM is linked to ataxia telangiectasia.