However, the Chronic Kidney Disease in Children (CKiD) study enrolled children with mild-to-moderate pre-dialysis CKD, respectively, concluded that a high plasma FGF23 concentration above 170 RU/ml together with estimated GFR ≥ 45 ml/min per 1.73 m2 is associated with a higher prevalence of LVH (85, 86). Here, FGF23 is linked to chronic kidney disease.