Barbus et al. (32) reported the statistically significant upregulation of FABP5 mRNA in tumors of short-term (<6 months) compared with long-term (>36 months) survivors of glioblastoma, the expression of which was associated with increased proliferation in the tumors and activation of 3-phosphoinositide-dependent protein kinase-1, indicating the tumorigenic involvement of FABP5 in this highly malignant and lethal brain cancer. This evidence concerns the gene PDPK1 and brain cancer.