ARTN and colorectal carcinoma: ARTN expression in CRC cells decreased protein levels of OCLN and increased protein levels of CDH2 and SNAIL: a small increase in expression of VIM with forced expression of ARTN was observed only in Caco2 and DLD1 cells but not in HCT116 cells (Figure 3H and Figure S6); whereas the opposite expression pattern of OCLN, CDH2 and SNAIL was observed with depletion of endogenous ARTN in CRC cells (Figure 3I).