Regarding the dynamic effects of HIF1A and OR7E156P on tumor growth, a subcutaneously implanted tumor model was constructed in nude mice by injecting glioma cells transduced with Adv-HIF1A (Adv-NC as control) and/or Lsh1-OR7E156P (Lsh-NC as control). The gene discussed is HIF1A; the disease is central nervous system cancer.