A differential expression analysis was performed in 10 cases of para-cancer control tissues and 197 cases of GBM tumor tissues from TCGA-GBM microarray dataset (AffyU133a) using an R language toolkit limma, and 8 differentially expressed ncRNAs were yielded (|logFC| > 0.4, P < 0.05), among which 3 were down-regulated (CDR1, MEG3, PART1) and 5, up-regulated (CYB561D2, DLEU1, DLEU2, HCP5, OR7E156P) (Figure S1). The gene discussed is CYB561D2; the disease is glioblastoma.