The AUC values of our plasma exosomal 2-miRNAs signature were more significant compared to the AUC values obtained for CEA (0.541, 95% CI: 0.463-0.627), CA19-9 (0.622, 95% CI 0.541-0.703) as well as their combination (0.567, 95% CI 0.485-0.650) to distinguish the GC patients from the controls (Figures 3F–H). Here, CEACAM5 is linked to gastric cancer.