More concretely, high CD86 expression of patients was related to a higher abundance of immune cells executing anti-tumor reactivity, including activated CD4+ T cells, activated CD8+ T cells, activated dendritic cells, central memory CD4+ T cells, central memory CD8+ T cells, effector memory CD4+ T cells, effector memory CD8+ T cells, natural killer cells, natural killer T cells, and type 1 T helper cells. Here, CD4 is linked to neoplasm.