Additionally, the expressions of SPARCL1, CP and TF differed significantly between stage IV colon cancer and normal (p < 0.05; Figures 8A–F), while that of SPARCL1, CDH2, CP and SERPINA5 differed significantly between rectum adenocarcinoma and normal tissues (Figures 8G–L). This evidence concerns the gene CDH2 and malignant colon neoplasm.