To investigate further whether CXCL10 in cervical cancer might be associated with epithelial atypical hyperplasia or carcinogenesis caused by HPV infection (29), HPV16 E6/E7 transgenic mice models, 8 founder lines, were established by breeding into C57BL/6×C57BL/6 hybrid mice. Here, CXCL10 is linked to cervical carcinoma.