BCR and type 1 diabetes mellitus: As it has been reported, these compounds are present in the plasma of diabetic patients in a concentration up to 1.2 μmol/L for CEL and 2.9 μmol/L for CML and at a concentration up to 1.7 μmol/L and 4.9 μmol/L, respectively, in the plasma in type I diabetes and impaired renal function patients [47].