NFE2L2 and myocardial infarction: Second, although PPARγ and PGC1α have been identified as potential targets for the protective effects of NOB against pathological cardiac remodeling after MI and we have initially verified that Nrf2/HO-1 could be the potential downstream effectors of PPARγ in the protective process, the interaction between them and whether other downstream effectors exist are worth further investigation.