These findings are consistent with previous findings which confirmed that MEG3 expression was found to be lower in clinical BC tissues compared with adjacent normal tissues, and MEG3 expression was found to be linked to differentiation grade, TNM stage, and lymph node metastasis in BC (Zhang et al., 2016; Mathias et al., 2019; Dong et al., 2021). This evidence concerns the gene MEG3 and breast cancer.