Xuefang et al. (2020) reported that miR-331-3p promoted apoptosis of nasopharyngeal carcinoma cells by targeting the elf4B-PI3K-AKT pathway, and Chen et al. (2018) recently reported that miR-331 inhibits the proliferation and invasion of melanoma cells. The gene discussed is AKT1; the disease is nasopharyngeal carcinoma.