TNK2 and colon adenocarcinoma: TNK2 expression across 24 cancer types in TCGA data was analyzed by UALCAN, independent-samples T test was used to analyze the significant differences between different cancers and their adjacent normal tissues, and the result shows that TNK2 expression was universally higher in most types of cancers, including breast cancer, COAD, and pancreatic cancer (Figure 1E).