(9) found that RANKL and RANK were expressed in both premalignant epithelium and tumor tissue in WT and mouse mammary tumor virus (MMTV)-RANK mice, which were implanted subcutaneously with medroxyprogesterone acetate (MPA), a strong progestin, and 7,12-dimethylbenzanthracene (DMBA), a carcinogen. The gene discussed is TNFRSF11A; the disease is neoplasm.