Because MMP-9, E-cadherin, N-cadherin, and vimentin have been implicated in preeclampsia pathogenesis, we investigated their relative expression by western blot analysis and found that collagen I significantly decreased MMP-9, vimentin, and N-cadherin expression, but increased E-cadherin protein levels (Figure 3D). The gene discussed is CDH1; the disease is preeclampsia.