We further constructed combined factors based on the above factors for assessing NAFLD risk, and the combined factor 1 (a combination of clinical factors) = (-1.588) + (-0.229) × age + 1.333 × visceral obesity + 0.484 × hypertension + 1.233 × hypertriglyceridemia + 0.621 × Low HDL-C + 0.939 × ALT. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.