For all participants with schizophrenia, prolactin level (B = 0.012, p < 0.001), concomitant antidepressant (B = 0.460, p < 0.001), HOMA-IR (B = 0.018, p = 0.001), duration of illness (B = 0.007, p = 0.008), and female sex (B = 0.0.127, p = 0.013) were associated with sexual dysfunction (Table 4). This evidence concerns the gene PRL and sexual dysfunction.