PLOD2 and central nervous system cancer: PLOD3 and PLOD2 are overexpressed and secreted by cells of lung cancer (Baek et al., 2018; Baek et al., 2019) glioma (Tsai et al., 2018), glioblastoma (Verano-Braga et al., 2018) and pancreatic duct adenocarcinoma (Schiarea et al., 2010).